The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 2020
Filed:
Aug. 26, 2016
Applicant:
Epizyme, Inc., Cambridge, MA (US);
Inventors:
Christine Klaus, Waban, MA (US);
Maria Alejandra Raimondi, Jamaica Plain, MA (US);
Scott R. Daigle, Newburyport, MA (US);
Roy MacFarlane Pollock, Medford, MA (US);
Assignee:
Epizyme, Inc., Cambridge, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7076 (2006.01); A61K 31/704 (2006.01); A61K 31/706 (2006.01); A61K 31/7068 (2006.01); A61K 31/4745 (2006.01); A61K 31/135 (2006.01); A61K 31/5377 (2006.01); A61K 31/136 (2006.01); A61K 31/635 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7076 (2013.01); A61K 31/135 (2013.01); A61K 31/136 (2013.01); A61K 31/4745 (2013.01); A61K 31/5377 (2013.01); A61K 31/635 (2013.01); A61K 31/704 (2013.01); A61K 31/706 (2013.01); A61K 31/7068 (2013.01);
Abstract
The present invention relates to compositions comprising inhibitors of human histone methyltransferase DOT1L and one or more therapeutic agents, particularly anticancer agents, and methods of combination therapy for administering to subjects in need thereof for the treatment of cancer.