The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 31, 2019

Filed:

May. 09, 2018
Applicant:

The Texas A&m University System, College Station, TX (US);

Inventors:

Po-Jung Huang, College Station, TX (US);

Gerard L. Coté, College Station, TX (US);

Mitchell B. Robinson, Willow Park, TX (US);

Jun Kameoka, College Station, TX (US);

Haley L. Marks, Brighton, MA (US);

Assignee:

The Texas A&M University System, College Station, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01J 3/44 (2006.01); G01N 21/65 (2006.01); G01N 1/34 (2006.01); B01L 3/00 (2006.01); G01N 33/553 (2006.01); G01N 33/543 (2006.01); G01N 1/40 (2006.01);
U.S. Cl.
CPC ...
G01N 21/658 (2013.01); B01L 3/502753 (2013.01); G01N 1/34 (2013.01); G01N 33/54326 (2013.01); G01N 33/54346 (2013.01); G01N 33/54366 (2013.01); G01N 33/553 (2013.01); B01L 2300/0654 (2013.01); B01L 2300/088 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0861 (2013.01); G01N 2001/4088 (2013.01); G01N 2021/651 (2013.01);
Abstract

There is a need in the point-of-care diagnostic community for an efficient and portable method for testing blood and other biological fluids that can be easily translated across multiple applications. An aspect of the invention described involves monitoring the optical properties of molecularly-mediated nanoparticle assemblies though an optically transparent and magnetically active microfluidic chip, which has recently emerged as an attractive method for biomarker detection as it is an efficient tool for monitoring the binding events that take place in a sensing assay. In one embodiment, this device is directed towards two-nanoparticle assays that rely on the assembly or disassembly of plasmonic and magnetic nanoparticles in response to a certain analyte. A further embodiment is directed to a spiral microfluidic using inertial forces to filter fluid components by size, connected to a magnetically active channel comprised of a nickel micropad array, optically transparent microchannel, and permanent magnets.


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