The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 31, 2019
Filed:
Jul. 02, 2018
Applicant:
Dsm Ip Assets B.v., Heerlen, NL;
Inventors:
Roelof Hendrik Matthijs Kouwen, Echt, NL;
Pim Van Hee, Echt, NL;
Douwe Van Sinderen, Carrigrohane, IE;
Brian McDonnell, Cork, IE;
Jennifer Mahony, Cork, IE;
Assignee:
DSM IP ASSETS B.V., Heerlen, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A23C 9/123 (2006.01); C12N 15/01 (2006.01); A23C 19/032 (2006.01); C12N 1/20 (2006.01); C12R 1/46 (2006.01); G16B 30/00 (2019.01); C12N 1/04 (2006.01); C12Q 1/689 (2018.01);
U.S. Cl.
CPC ...
C12R 1/46 (2013.01); A23C 9/1238 (2013.01); A23C 19/0323 (2013.01); C12N 1/04 (2013.01); C12N 1/20 (2013.01); C12N 15/01 (2013.01); C12Q 1/689 (2013.01); G16B 30/00 (2019.02); A23Y 2240/75 (2013.01);
Abstract
Bacteriophage Insensitive Mutants (BIMs) of threeparent strains were generated and characterized for phage sensitivity, sedimentation rate, cell chain length, phage adsorption and CRISPR loci alterations. Several BIMs showed an altered sedimentation phenotype as well as an increase cell chain length, reduced phage sensitivity, reduced phage adsorption and 100% identity in three CRISPR loci. The results show that the derived BIMs have become phage-resistant through a mechanism other than CRISPR.