The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 31, 2019
Filed:
Dec. 18, 2014
Applicant:
Jiangsu Micromedmark Biotech Co., Ltd., Jiangsu, CN;
Inventors:
Chenyu Zhang, Beijing, CN;
Ke Zeng, Beijing, CN;
Yuan Yin, Beijing, CN;
Xing Cai, Jiangsu, CN;
Junfeng Zhang, Jiangsu, CN;
Assignee:
Jiangsu Micromedmark Biotech Co., Ltd., Jiangsu, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 15/11 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 15/113 (2010.01); C12Q 1/6876 (2018.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C12Q 1/6876 (2013.01); C12N 2310/113 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/158 (2013.01);
Abstract
Provided is a use of miRNA-214 inhibitor in inhibiting regulatory T cells (Treg cells). The microRNA-214 (miRNA-214) can promote Treg cells, and can assist tumors in immune escape. The experiments demonstrates that the inhibition of miRNA-214 can inhibit the growth of Treg cells, thus inhibiting the growth of tumors. Therefore, miRNA-214 can be used for developing an anti-tumour drug or a drug inhibiting immune response hyperactivity.