The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 31, 2019
Filed:
Jun. 15, 2018
Applicant:
Apogenix Ag, Heidelberg, DE;
Inventors:
Oliver Hill, Neckarsteinach, DE;
Christian Gieffers, Dossenheim, DE;
Meinolf Thiemann, Schriesheim, DE;
Marcus Branschaedel, Heidelberg, DE;
Assignee:
APOGENIX AG, Heidelberg, DE;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); C07K 14/525 (2006.01); C12N 15/62 (2006.01); C07K 14/42 (2006.01); C07K 14/47 (2006.01); C07K 19/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70575 (2013.01); C07K 14/42 (2013.01); C07K 14/47 (2013.01); C07K 14/4726 (2013.01); C07K 14/525 (2013.01); C07K 19/00 (2013.01); C12N 15/62 (2013.01); C07K 2319/00 (2013.01); C07K 2319/02 (2013.01); C07K 2319/21 (2013.01); C07K 2319/22 (2013.01); C07K 2319/32 (2013.01); C07K 2319/70 (2013.01);
Abstract
The present invention refers to a fusion protein comprising a TNF-superfamily (TNFSF) cytokine or a receptor binding domain thereof fused to a collectin trimerization domain, to a nucleic acid molecule encoding the fusion protein, and to a cell comprising the nucleic acid molecule. The fusion protein is present as a trimeric complex or as an oligomer thereof. The fusion protein, the nucleic acid, and the cell is suitable as pharmaceutical composition or for therapeutic, diagnostic and/or research applications.