The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 31, 2019
Filed:
Jan. 30, 2019
Applicants:
The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);
The General Hospital Corporation, Boston, MA (US);
Inventors:
Gianpietro Dotti, Chapel Hill, NC (US);
Soldano Ferrone, Boston, MA (US);
Hongwei Du, Chapel Hill, NC (US);
Xinhui Wang, Boston, MA (US);
Cristina Ferrone, Boston, MA (US);
Assignees:
The University of North Carolina at Chapel Hill, Chapel Hill, NC (US);
The General Hospital Corporation, Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); A61P 35/00 (2006.01); G01N 33/574 (2006.01); A61K 35/17 (2015.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70521 (2013.01); A61K 35/17 (2013.01); A61P 35/00 (2018.01); C07K 14/70532 (2013.01); C07K 14/70596 (2013.01); G01N 33/574 (2013.01); G01N 33/57492 (2013.01); A61K 38/00 (2013.01);
Abstract
The present invention provides a chimeric antigen receptor (CAR) that recognizes B7-H3 (CD276), as well as methods of use in the treatment of diseases and disorders.