The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 31, 2019

Filed:

Dec. 29, 2016
Applicant:

Shenzhen Targetrx, Inc., Shenzhen, CN;

Inventors:

Yihan Wang, Shenzhen, CN;

Xingye Ren, Shenzhen, CN;

Assignee:

Shenzhen TargetRx, Inc., Shenzhen, Guangdong, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 35/00 (2006.01); C07J 43/00 (2006.01); C07J 1/00 (2006.01); C07J 13/00 (2006.01); C07J 41/00 (2006.01);
U.S. Cl.
CPC ...
C07J 43/003 (2013.01); A61P 35/00 (2018.01); C07B 2200/05 (2013.01); C07J 1/0011 (2013.01); C07J 13/005 (2013.01); C07J 41/0005 (2013.01);
Abstract

Disclosed are a steroidal compound as shown in formula (I) and a drug composition containing the same, or a crystal form, a pharmaceutically acceptable salt, a hydrate or solvate, a stereoisomer, a prodrug, a metabolite or an isotopic variant thereof. The compound can be used as a CYP17 enzyme inhibitor, and has better pharmacokinetic parameters, which can improve drug concentration of the compound in an animal, thereby improving the efficacy and safety of the drug, and in turn the compound may be applied in the preparation of the drug for treating CYP17 enzyme-related diseases (such as prostate cancer).


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