The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 31, 2019

Filed:

Feb. 08, 2019
Applicant:

X-cutag Therapeutics, Inc., Framingham, MA (US);

Inventors:

Hui Joyce Li, Westborough, MA (US);

Shuhao Wen, Andover, MA (US);

Changfu Cheng, Northborough, MA (US);

Xiao Chen, Princeton, NJ (US);

Gao Shang, Doylestown, PA (US);

Assignee:

X-CUTAG THERAPEUTICS, INC., Framingham, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 453/00 (2006.01); A61K 31/439 (2006.01); C07D 471/08 (2006.01);
U.S. Cl.
CPC ...
C07D 471/08 (2013.01); C07B 2200/05 (2013.01);
Abstract

Novel deuterium-containing chemical compounds are provided. They are glucosylceramide (GSC) synthase inhibitors and are useful for treating various types of lysosomal storage diseases including Fabry's disease, Gaucher's disease and Parkinson's disease, or related diseases and conditions. Also described are pharmaceutical compositions, and methods of preparation and use thereof.


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