The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 31, 2019
Filed:
Dec. 15, 2016
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Thomas J. Greshock, Collegeville, PA (US);
James Mulhearn, Elkins Park, PA (US);
Liangqin Guo, Edison, NJ (US);
Ting Zhang, Princeton Junction, NJ (US);
Deping Wang, Furlong, PA (US);
Ronald M. Kim, Summit, NJ (US);
Mark E. Layton, Harleysville, PA (US);
Michael J. Kelly, Iii, Paoli, PA (US);
Rajan Anand, Fanwood, NJ (US);
Philippe Nantermet, Landsdale, PA (US);
Tianying Jian, Westfield, NJ (US);
Anthony J. Roecker, Harleysville, PA (US);
Walter Won, Alpine, NJ (US);
Gang Zhou, Bridgewater, NJ (US);
Thomas J. Greshock, Collegeville, PA (US);
James Mulhearn, Elkins Park, PA (US);
Liangqin Guo, Edison, NJ (US);
Ting Zhang, Princeton Junction, NJ (US);
Deping Wang, Furlong, PA (US);
Ronald M. Kim, Summit, NJ (US);
Mark E. Layton, Harleysville, PA (US);
Michael J. Kelly, III, Paoli, PA (US);
Rajan Anand, Fanwood, NJ (US);
Philippe Nantermet, Landsdale, PA (US);
Tianying Jian, Westfield, NJ (US);
Anthony J. Roecker, Harleysville, PA (US);
Walter Won, Alpine, NJ (US);
Gang Zhou, Bridgewater, NJ (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
Disclosed are compounds of Formula A, or a salt thereof, where Q, X, R1 and R2 are as defined herein, which compounds have properties for inhibiting Na1.7 ion channels found in peripheral and sympathetic neurons. Also described are pharmaceutical formulations comprising the compounds of Formula A or their salts, and methods of treating pain (acute, post-operative, neuropathic), or cough or itch disorders using the same.