The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 31, 2019

Filed:

Mar. 24, 2017
Applicants:

Luoxin Pharmaceutical (Shanghai) Co., Ltd, Shanghai, CN;

Shandong Luoxin Pharmaceutical Group Stock Co., Ltd., Linyi, CN;

Inventors:

Jianyu Lu, Shanghai, CN;

Charles Z. Ding, Shanghai, CN;

Lihong Hu, Shanghai, CN;

Huijun He, Shanghai, CN;

Shuhui Chen, Shanghai, CN;

Jiaqiang Dong, Shanghai, CN;

Tie-Lin Wang, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/437 (2006.01); C07D 409/06 (2006.01); C07D 403/12 (2006.01); A61K 31/404 (2006.01); C07D 209/18 (2006.01); C07D 401/06 (2006.01); C07D 405/06 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 409/06 (2013.01); A61K 31/404 (2013.01); C07D 209/18 (2013.01); C07D 401/06 (2013.01); C07D 403/12 (2013.01); C07D 405/06 (2013.01); A61P 35/00 (2018.01);
Abstract

Disclosed is a new indole compound, in particular, the compound as shown in formula (I), and a preparation method, pharmaceutical composition and use thereof as an estrogen receptor down-regulator in preparing drugs for treating estrogen receptor-positive breast cancer.


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