The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 31, 2019
Filed:
Dec. 26, 2017
Applicant:
Apicore Us Llc, Somerset, NJ (US);
Inventors:
Ravishanker Kovi, Monroe, NJ (US);
Jayaraman Rao Kannapan, Vadodara, IN;
Ananda Babu Thirunavakarasu, Gujarat, IN;
Veerabhadra Rao Bobbili, Andhra Pradesh, IN;
Gaurav Yadav, Utter Pradesh, IN;
Assignee:
Apicore US LLC, Canonsburg, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 295/096 (2006.01); A61K 31/496 (2006.01);
U.S. Cl.
CPC ...
C07D 295/096 (2013.01); A61K 31/496 (2013.01); C07B 2200/13 (2013.01);
Abstract
Processes are disclosed for making vortioxetine and pharmaceutically acceptable salts thereof. A propylene glycol solvate of vortioxetine hydrobromide is disclosed. A novel crystalline form of vortioxetine hydrobromide propylene glycol solvate, designated form AC1, is disclosed along with a method for making same. Form AC1 may be characterized by an x-ray powder diffraction pattern with peaks at about 19.64, 22.85, 25.51, 29.57, 30.18±0.2 degrees 2-theta.