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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10519110 B1

PDFFull Text
Date of Patent:
Dec. 31, 2019

Filed:

Oct. 30, 2018

Heterocyclic compound

Applicant:

Takeda Pharmaceutical Company Limited, Osaka, JP;

Inventors:

Yasutomi Asano, Fujisawa, JP;

Takuto Kojima, Fujisawa, JP;

Osamu Kurasawa, Fujisawa, JP;

Tzu-Tshin Wong, Acton, MA (US);

Yasuhiro Hirata, Fujisawa, JP;

Naoki Iwamura, Fujisawa, JP;

Bunnai Saito, Fujisawa, JP;

Yuta Tanaka, Fujisawa, JP;

Ryosuke Arai, Fujisawa, JP;

Shinichi Imamura, Fujisawa, JP;

Kazuko Yonemori, Fujisawa, JP;

Yasufumi Miyamoto, Fujisawa, JP;

Shuji Kitamura, Fujisawa, JP;

Osamu Sano, Fujisawa, JP;

Assignee:

TAKEDA PHARMACEUTICAL COMPANY LIMITED, Osaka, JP;

Attorneys:

Casimir Jones, S.C.

Anne M. Reynolds

Primary Examiner:

Zinna Northington Davis

Int. Cl.
CPC ...
C07D 211/58 (2006.01); C07F 9/6509 (2006.01); C07D 401/14 (2006.01); A61K 31/437 (2006.01); A61K 31/443 (2006.01); A61K 31/4433 (2006.01); A61K 31/4436 (2006.01); A61K 31/4439 (2006.01); A61K 31/444 (2006.01); A61K 31/4468 (2006.01); A61K 31/451 (2006.01); A61K 31/452 (2006.01); A61K 31/4709 (2006.01); A61K 31/498 (2006.01); A61K 31/506 (2006.01); A61K 31/517 (2006.01); A61K 31/5355 (2006.01); A61K 31/661 (2006.01); A61K 33/22 (2006.01); C07D 215/42 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01); C07D 409/12 (2006.01); C07D 413/06 (2006.01); C07D 417/06 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 498/04 (2006.01); C07D 513/04 (2006.01); C07D 519/00 (2006.01); C07F 5/02 (2006.01); A61P 3/00 (2006.01); A61P 35/00 (2006.01); C07B 59/00 (2006.01); C07D 405/06 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
C07D 211/58 (2013.01); A61K 31/437 (2013.01); A61K 31/443 (2013.01); A61K 31/444 (2013.01); A61K 31/4433 (2013.01); A61K 31/4436 (2013.01); A61K 31/4439 (2013.01); A61K 31/4468 (2013.01); A61K 31/451 (2013.01); A61K 31/452 (2013.01); A61K 31/4709 (2013.01); A61K 31/498 (2013.01); A61K 31/506 (2013.01); A61K 31/517 (2013.01); A61K 31/5355 (2013.01); A61K 31/661 (2013.01); A61K 33/22 (2013.01); A61P 3/00 (2018.01); A61P 35/00 (2018.01); C07B 59/002 (2013.01); C07D 215/42 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 405/06 (2013.01); C07D 409/12 (2013.01); C07D 413/06 (2013.01); C07D 413/14 (2013.01); C07D 417/06 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 498/04 (2013.01); C07D 513/04 (2013.01); C07D 519/00 (2013.01); C07F 5/02 (2013.01); C07F 9/6509 (2013.01); C07B 2200/05 (2013.01); Y02P 20/55 (2015.11);
Abstract

The present invention relates to a compound which can be useful for the treatment or prevention of SPT-related diseases including cancer and congenital diseases associated with sphingolipid accumulation (including Niemann-Pick disease).

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