The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 31, 2019
Filed:
Feb. 28, 2017
Applicant:
Nerpharma S.r.l., Nerviano (Milan), IT;
Inventors:
Attilio Tomasi, Milan, IT;
Ilaria Candiani, Busto Arsizio, IT;
Francesco Corcella, Busto Garolfo, IT;
Francesco Saverio Caldarelli, Milan, IT;
Assignee:
NerPharMa S.r.l., Nerviano (Milan), IT;
Primary Examiner:
Int. Cl.
CPC ...
C07C 273/18 (2006.01); C07C 275/08 (2006.01); C07C 275/68 (2006.01); C07D 233/60 (2006.01);
U.S. Cl.
CPC ...
C07C 273/1854 (2013.01); C07C 273/1809 (2013.01); C07C 273/1836 (2013.01); C07C 275/08 (2013.01); C07C 275/68 (2013.01); C07D 233/60 (2013.01);
Abstract
Carmustine may be safely and efficiently produced by reacting 2-chloroethylamine hydrochloride and 1,1'-carbonyldiimidazole to afford 1,3-bis(2-chloroethyl)-1-urea, followed by nitrosation to give the final product.