The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 31, 2019

Filed:

Jul. 16, 2016
Applicant:

Bowling Green State University, Bowling Green, OH (US);

Inventors:

Alexis Ostrowski, Maumee, OH (US);

Giuseppe Giammanco, Bowling Green, OH (US);

Assignee:

Bowling Green State University, Bowling Green, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/52 (2006.01); A61L 27/04 (2006.01); A61L 27/26 (2006.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
A61L 27/52 (2013.01); A61L 27/04 (2013.01); A61L 27/26 (2013.01); C12N 5/0068 (2013.01); A61L 2400/18 (2013.01); A61L 2430/34 (2013.01); C12N 2533/74 (2013.01); C12N 2535/00 (2013.01);
Abstract

Uronate-containing polysaccharide hydrogels that can be photo-patterned are described. The method involves forming a hydrogel and imetal-coordinating it with a reducible metallic cation and exposing the hydrogel to light in a desired pattern. The exposure to light reduces the metallic cation and results in an irreversible change in the elastic moduli and pore size of the irradiated portions of the patterned hydrogel. The method aha the benefit of allowing the user to produce such a hydrogel in any pattern desired. Patterned hydrogels and cell substrates formed by this method are also described.


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