The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 31, 2019

Filed:

Feb. 16, 2016
Applicant:

University of Maryland, College Park, College Park, MD (US);

Inventors:

Christopher M. Jewell, Silver Spring, MD (US);

Lisa H. Tostanoski, Washington, DC (US);

Yu-Chieh Chiu, College Park, MD (US);

Assignee:

University of Maryland, College Park, College Park, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/39 (2006.01); A61K 39/00 (2006.01); A61K 9/16 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39 (2013.01); A61K 9/1611 (2013.01); A61K 9/1676 (2013.01); A61K 39/00 (2013.01); A61K 39/0008 (2013.01); A61K 2039/55555 (2013.01); A61K 2039/55561 (2013.01); A61K 2039/57 (2013.01); A61K 2039/572 (2013.01); A61K 2039/575 (2013.01); A61K 2039/577 (2013.01);
Abstract

Immune-polyelectrolyte multilayers (iPEMs) that can be made entirely from immune signal compounds are provided. The iPEMs are formed from first layer of a first immune signal compound, and a second layer of the first immune signal compound or a second immune signal compound disposed on the first layer of the first immune signal compound. The immune signal compounds are peptides, polypeptides, nucleic acids, charged derivatives thereof. Combinations of the immune signal compounds may be in adjacent layers. The first immune signal compound and the second immune signal compound have oppositely charged domains. iPEMs can be formed on or include a substrate, such as a sacrificial substrate, which allows for the formation of a three-dimensional void which can hold various other compounds for use in modulating immune responses. The iPEMs are for use in either stimulating an immune response to one or more antigens, or inducing tolerance to one or more antigens. Methods of stimulating immune responses, or inducing tolerance using the iPEMs, are also provided.


Find Patent Forward Citations

Jewell, Christopher. (2019). Polyelectrolyte multilayers assembled from immune signal compounds (U.S. Patent No. 10517946). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10517946

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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