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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10517935 B1

PDFFull Text
Date of Patent:
Dec. 31, 2019

Filed:

Dec. 12, 2016

Mimotopes of alpha-synuclein and vaccines thereof for the treatment of neurodegenerative disorders

Applicant:

Affiris Ag, Vienna, AT;

Inventors:

Markus Mandler, Vienna, AT;

Harald Weninger, Vienna, AT;

Radmila Santic, Vienna, AT;

Edith Kopinits, Landegg, AT;

Assignee:

AFFIRIS AG, Vienna, AT;

Attorney:

Oblon, McClelland, Maier & Neustadt, L.L.P.

Primary Examiner:

Chang-Yu Wang

Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 49/00 (2006.01); A61K 38/17 (2006.01); C07K 14/47 (2006.01); C07K 14/00 (2006.01); C07K 4/00 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); C07K 2/00 (2006.01); A61B 5/00 (2006.01); A61K 39/00 (2006.01); C07K 16/42 (2006.01); A61K 9/00 (2006.01); A61K 47/02 (2006.01); A61K 47/64 (2017.01); A61K 39/395 (2006.01); A61K 39/385 (2006.01); G01N 33/68 (2006.01); C07K 16/18 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); A61P 25/28 (2006.01); A61P 25/16 (2006.01); A61K 31/00 (2006.01); A61K 47/42 (2017.01); A61K 47/69 (2017.01);
U.S. Cl.
CPC ...
A61K 39/0007 (2013.01); A61K 9/0019 (2013.01); A61K 38/1709 (2013.01); A61K 47/02 (2013.01); A61K 47/643 (2017.08); C07K 14/47 (2013.01); C07K 16/4241 (2013.01); A61K 9/0053 (2013.01); A61K 31/00 (2013.01); A61K 38/00 (2013.01); A61K 39/385 (2013.01); A61K 39/3955 (2013.01); A61K 47/42 (2013.01); A61K 47/6911 (2017.08); A61K 2039/505 (2013.01); A61K 2039/55505 (2013.01); A61K 2039/55516 (2013.01); A61K 2039/55555 (2013.01); A61K 2039/55566 (2013.01); A61K 2039/55572 (2013.01); A61K 2039/57 (2013.01); A61K 2039/575 (2013.01); A61K 2039/58 (2013.01); A61K 2039/6031 (2013.01); A61K 2039/6081 (2013.01); A61K 2039/70 (2013.01); A61P 25/16 (2018.01); A61P 25/28 (2018.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); C07K 16/18 (2013.01); C07K 2317/21 (2013.01); C07K 2317/32 (2013.01); C07K 2317/33 (2013.01); C07K 2317/622 (2013.01); C07K 2317/76 (2013.01); C07K 2319/00 (2013.01); G01N 33/6896 (2013.01); G01N 2800/52 (2013.01);
Abstract

A method of treating a synucleinopathy with a peptide (C)DQPVLPD (SEQ ID NO: 59), (C)DMPVLPD (SEQ ID NO: 60), (C)DSPVLPD (SEQ ID NO: 61), (C)DQPVLPDN (SEQ ID NO: 64), (C)DMPVLPDN (SEQ ID NO: 65), (C)DSPVLPDN (SEQ ID NO: 66), (C)HDRPVTPD (SEQ ID NO: 70), (C)DRPVTPD (SEQ ID NO: 71), (C)DVPVLPD (SEQ ID NO: 72), (C)DTPVYPD (SEQ ID NO: 73), (C)DTPVIPD (SEQ ID NO: 74), (C)HDRPVTPDN (SEQ ID NO: 75), (C)DRPVTPDN (SEQ ID NO: 76), (C)DVPVLPDN (SEQ ID NO: 78), (C)DTPVYPDN (SEQ ID NO: 79), (C)DQPVLPDG (SEQ ID NO: 81), (C)DMPVLPDG (SEQ ID NO: 82), (C)DSPVLPDG (SEQ ID NO: 83), (C)DHPVHPDS (SEQ ID NO: 86), (C)DMPVSPDR (SEQ ID NO: 87), (C)DRPVYPDI (SEQ ID NO: 90), (C)DHPVTPDR (SEQ ID NO: 91), (C)DTPVLPDS (SEQ ID NO: 93), (C)DMPVTPDT (SEQ ID NO: 94), (C)DAPVTPDT (SEQ ID NO: 95), (C)DSPVVPDN (SEQ ID NO: 96), (C)DLPVTPDR (SEQ ID NO: 97), (C)DSPVHPDT (SEQ ID NO: 98), (C)DAPVRPDS (SEQ ID NO: 99), (C)DMPVLPDG (SEQ ID NO: 100), (C)DRPVQPDR (SEQ ID NO: 102), (C)YDRPVQPDR (SEQ ID NO: 103), (C)DMPVDADN (SEQ ID NO: 105), DQPVLPD(C) (SEQ ID NO: 106), and DMPVLPD(C) (SEQ ID NO: 107.

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