The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 31, 2019
Filed:
Mar. 14, 2018
Applicant:
Los Angeles Biomedical Research Institute AT Harbor-ucla Medical Center, Torrance, CA (US);
Inventors:
Omid Khorram, Rolling Hills, CA (US);
Tsai-Der Chuang, Inglewood, CA (US);
Assignee:
Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/196 (2006.01); C12Q 1/6883 (2018.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/196 (2013.01); A61P 35/00 (2018.01); C12Q 1/6883 (2013.01); C12Q 2600/178 (2013.01);
Abstract
Methods of modulating a miRNA level, such as a miR-29c and/or miR-200c level, in a cell are provided. Aspects of the methods include contacting the cell with an anti-fibrotic miRNA modulating active agent, such as a tranilast active agent. Also provided are compositions for use in practicing the methods. The methods and compositions find use in a variety of applications, including the treatment of fibrotic disorders, such as a uterine leiomyoma.