The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 31, 2019
Filed:
Apr. 09, 2019
Massachusetts Institute of Technology, Cambridge, MA (US);
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Andrew Bellinger, Wellesley, MA (US);
Shiyi Zhang, Shanghai, CN;
Carlo Giovanni Traverso, Newton, MA (US);
Robert S. Langer, Newton, MA (US);
Stacy Mo, Darien, IL (US);
Tyler Grant, Arlington, MA (US);
Mousa Jafari, Waltham, MA (US);
Dean Liang Glettig, Cambridge, MA (US);
Angela DiCiccio, San Francisco, CA (US);
Lowell L. Wood, Jr., Bellevue, WA (US);
Philip A. Eckhoff, Kirkland, WA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Tokitae LLC, Bellevue, WA (US);
Abstract
Described are methods of making a gastric residence structure including an active substance. The methods may include forming one or more arms comprising a loadable polymeric component, wherein the loadable polymeric component includes one or more polymeric materials and at least one active substance. The methods may also include connecting the one or more arms to an elastic polymeric component using a separate linker component. The gastric residence structures may be configured to be folded and physically constrained during administration and may be configured to assume an open retention shape upon removal of a constraint. The change between the folded shape and the open retention shape may be mediated by the elastic polymeric component that undergoes elastic deformation when the residence structure is in the folded shape and recoils when the gastric residence structure assumes the open retention shape.