The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 24, 2019

Filed:

Oct. 25, 2012
Applicant:

Infandx Ag, Cologne, DE;

Inventors:

Matthias Keller, Essen, DE;

David Enot, Creully, FR;

Assignee:

InfanDx AG, Köln, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); G01N 27/447 (2006.01); G16B 20/00 (2019.01); G16C 20/70 (2019.01);
U.S. Cl.
CPC ...
G01N 33/6896 (2013.01); G01N 27/447 (2013.01); G01N 2800/28 (2013.01); G01N 2800/38 (2013.01); G01N 2800/60 (2013.01); G16B 20/00 (2019.02); G16C 20/70 (2019.02);
Abstract

Metabolites and signatures (panels) of metabolites are applicable as biomarkers in clinical diagnosis, in particular for neonatal encephalopathy. They are useful tools in differential clinical diagnosis for early detection of brain injury, determination of brain areas affected by the insults and prediction of adverse neurological outcome and may also be applied in diagnosing disease progression and treatment effect. An in vitro method for predicting the likelihood of neonatal encephalopathy of distinct brain areas, identification of affected brain area(s) of neonatal encephalopathy and risk of brain damage and prognosis and neurological outcome due to identification of the type and extent of damage of distinct brain tissues, in particular of hippocampus and/or basal ganglia, is provided.


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