The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 24, 2019

Filed:

Nov. 16, 2016
Applicant:

Government of United States of America, As Represented BY Secretary, Gaithersburg, MD (US);

Inventors:

Darwin R. Reyes-Hernandez, Clarksburg, MD (US);

Brian Nablo, Rockville, MD (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 27/447 (2006.01); G01N 33/483 (2006.01); B03C 5/00 (2006.01); B03C 5/02 (2006.01);
U.S. Cl.
CPC ...
G01N 27/44773 (2013.01); B03C 5/005 (2013.01); B03C 5/026 (2013.01); G01N 27/447 (2013.01); G01N 27/44747 (2013.01); G01N 33/4836 (2013.01); B03C 2201/26 (2013.01);
Abstract

A dual dielectropheretic article for monitoring cell migration includes: a membrane to selectively migrate a plurality of cells across the membrane, the membrane including: a first surface to receive the cells; a second surface opposed to the first surface; and a plurality of communication paths disposed in the membrane to provide the selective migration of the cells across the membrane from the first surface to the second surface; a first electrode disposed on the first surface to: provide an electric field for dielectrophoresis of the cells at the first surface; and provide a first potential for monitoring an impedance at the first surface; and a third electrode disposed on the second surface to: provide an electric field for dielectrophoresis of the cells at the second surface; and provide a third potential for monitoring an impedance at the second surface.


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