The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 24, 2019

Filed:

Oct. 02, 2017
Applicant:

Shin-etsu Chemical Co., Ltd., Tokyo, JP;

Inventors:

Yasuyuki Hirama, Joetsu, JP;

Aya Tsuchiya, Yokohama, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08B 11/08 (2006.01); A61K 9/20 (2006.01); A61K 47/38 (2006.01); C08B 3/08 (2006.01); C08B 3/14 (2006.01); C08B 11/193 (2006.01); G01N 23/20 (2018.01); A61K 9/14 (2006.01); C09D 101/30 (2006.01); C08L 1/32 (2006.01);
U.S. Cl.
CPC ...
C08B 3/08 (2013.01); A61K 9/2054 (2013.01); C08B 3/14 (2013.01); C08B 11/08 (2013.01); C08B 11/193 (2013.01); A61K 9/146 (2013.01); A61K 47/38 (2013.01); C08L 1/32 (2013.01); C09D 101/30 (2013.01); G01N 23/20 (2013.01);
Abstract

Provided are low-substituted hydroxypropyl cellulose (L-HPC) having a hydroxypropoxy content of from 5 to 16% by weight, and having, on a basis of a dynamic image analysis to divide all particles into fine, spherical, and fibrous particles consisting of long and short fibrous particles, a volume fraction of the long fibrous particles of from 15 to 50% and a volume fraction of the short fibrous particles of from 23 to 60%; and a solid preparation containing the L-HPC. Also provided is a method for producing the L-HPC including the steps: bringing sheet-like or chip-like pulp having a length-weighted average fiber length of from 2.40 to 3.50 mm into contact with an alkali metal hydroxide solution, reacting the resulting alkali cellulose with propylene oxide, and dispersing the resulting reaction product in water containing an acid to partially dissolve it therein, followed by neutralization with an acid to precipitate crude L-HPC.


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