The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 24, 2019

Filed:

Oct. 26, 2015
Applicant:

New York University, New York, NY (US);

Inventors:

Xiaojin He, New York City, NY (US);

Ruojie Sha, Basking Ridge, NJ (US);

Yongli Mi, Kowloon, HK;

Paul Chaikin, New York, NY (US);

Nadrian C. Seeman, New York, NY (US);

Assignee:

NEW YORK UNIVERSITY, New York, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 19/34 (2006.01); C07H 21/04 (2006.01); C12Q 1/6816 (2018.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C07H 21/04 (2013.01); C12N 15/11 (2013.01); C12Q 1/6816 (2013.01);
Abstract

The present invention provides a method for self-replication of multimers of nucleic acid origami tiles by exponentially amplifying the multimer from initial seeds of monomeric units of nucleic acid origami tiles and also provides for the selective exponential amplification of a designated multimer, such as with specific properties or characteristics, over one or more competing multimers in the presence of a mixture of monomers for each of the possible multimers. The selection of the designated multimer based on an environmental change allows the designated multimer to outgrow all competing multimers.


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