The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 24, 2019

Filed:

Jan. 16, 2018
Applicant:

The United States of America, As Represented BY the Secretary of Agriculture, Washington, DC (US);

Inventor:

Neil P. Price, Edelstein, IL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/06 (2006.01); A61K 31/7072 (2006.01); A61P 31/04 (2006.01); A01N 43/54 (2006.01); A01N 43/90 (2006.01); A61K 31/7034 (2006.01); A01N 43/16 (2006.01); C07H 19/16 (2006.01); A61K 31/7076 (2006.01); A01N 57/16 (2006.01); A61K 45/06 (2006.01); C07H 15/207 (2006.01);
U.S. Cl.
CPC ...
C07H 19/06 (2013.01); A01N 43/16 (2013.01); A01N 43/54 (2013.01); A01N 43/90 (2013.01); A01N 57/16 (2013.01); A61K 31/7034 (2013.01); A61K 31/7072 (2013.01); A61K 31/7076 (2013.01); A61P 31/04 (2018.01); C07H 15/207 (2013.01); C07H 19/16 (2013.01); A61K 45/06 (2013.01);
Abstract

Tunicamycin related compounds having an acyl chain double bond reduced and/or having an acyl chain double bond and an uracil ring double bond reduced are described as well as methods of making these tunicamycin related compounds. These tunicamycin related compounds are not toxic to eukaryotic cells and can be used to kill Gram-positive bacteria, alone or in combination with other antibiotics. Use of these tunicamycin related compounds to kill Gram-positive bacteria, treat Gram-positive bacterial diseases, and disinfect objects or surfaces are described. In addition, naturally-occurring streptovirudin compounds are not toxic to eukaryotic cells and can be used to kill Gram-positive bacteria, alone or in combination with other antibiotics.


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