The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 24, 2019

Filed:

Jun. 15, 2016
Applicant:

The Brigham and Women's Hospital, Inc., Boston, MA (US);

Inventors:

Shiladitya Sengupta, Waltham, MA (US);

Abhimanyu Paraskar, Belmont, MA (US);

Shivani Soni, La Canada Flintridge, CA (US);

Sudipta Basu, Cambridge, MA (US);

Poulomi Sengupta, Belmont, MA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 33/24 (2019.01); A61K 31/282 (2006.01); C08F 8/32 (2006.01); C07J 41/00 (2006.01); A61K 47/48 (2006.01); A61K 31/382 (2006.01); A61K 47/24 (2006.01); A61K 47/16 (2006.01); C08F 22/06 (2006.01); C08F 222/06 (2006.01); A61K 47/60 (2017.01); A61K 47/54 (2017.01); A61K 47/58 (2017.01); A61K 47/69 (2017.01);
U.S. Cl.
CPC ...
A61K 47/489 (2013.01); A61K 31/282 (2013.01); A61K 31/382 (2013.01); A61K 33/24 (2013.01); A61K 47/16 (2013.01); A61K 47/24 (2013.01); A61K 47/543 (2017.08); A61K 47/544 (2017.08); A61K 47/58 (2017.08); A61K 47/60 (2017.08); A61K 47/6933 (2017.08); C07J 41/0055 (2013.01); C08F 8/32 (2013.01); C08F 22/06 (2013.01); C08F 222/06 (2013.01);
Abstract

The invention is directed to biocompatible conjugated polymer nanoparticles including a copolymer backbone, a plurality of sidechains covalently linked to said backbone, and a plurality of platinum compounds dissociably linked to said backbone. The invention is also directed to dicarbonyl-lipid compounds wherein a platinum compound is dissociably linked to the dicarbonyl compound. The invention is also directed to methods of treating cancer or metastasis. The methods includes selecting a subject in need of treatment for cancer or metastasis and administering to the subject an effective amount of any of the nanoparticles, compounds, or compositions of the invention.


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