The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 24, 2019

Filed:

Mar. 31, 2017
Applicants:

Colorado State University Research Foundation, Fort Collins, CO (US);

The Regents of the University of Colorado, a Body Corporate, Denver, CO (US);

Inventors:

Steven Dow, Littleton, CO (US);

Michael R. Lappin, Fort Collins, CO (US);

William H. Wheat, Fort Collins, CO (US);

Lyndah Chow, Fort Collins, CO (US);

Daniel P. Regan, Fort Collins, CO (US);

Thomas J. Anchordoquy, Lakewood, CO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 8/14 (2006.01); A61K 39/39 (2006.01); C12N 15/117 (2010.01); A61K 47/69 (2017.01); A61K 39/12 (2006.01); A61K 49/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39 (2013.01); A61K 8/14 (2013.01); A61K 39/12 (2013.01); A61K 47/6911 (2017.08); C12N 15/117 (2013.01); A61K 49/0054 (2013.01); A61K 49/0084 (2013.01); A61K 2039/53 (2013.01); A61K 2039/543 (2013.01); A61K 2039/545 (2013.01); A61K 2039/552 (2013.01); A61K 2039/555 (2013.01); A61K 2039/55511 (2013.01); A61K 2039/55516 (2013.01); A61K 2039/55555 (2013.01); A61K 2039/55561 (2013.01); A61K 2039/57 (2013.01); C12N 2710/16034 (2013.01);
Abstract

The disclosed compositions and methods relate to an immunogenic composition that, in certain aspects, comprise cationic liposomes; a mixture of toll like receptor 3 (TLR3) and toll like receptor 9 (TLR9) ligands; and a cellular adhesion agent, and methods of using such compositions. In certain aspects, disclosed compositions are administered to a mammal to induce a non-specific innate immune response at mucosal surfaces. In further aspects, disclosed compositions are administered to a mammal in conjunction with an antigen to enhance the immune response of the mammal to the antigen.


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