The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 24, 2019
Filed:
Sep. 25, 2015
Applicant:
Bavarian Nordic A/s, Kvistgaard, DK;
Inventors:
Assignee:
Bavarian Nordic A/S, Kvistgaard, DK;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/285 (2006.01); A61K 39/39 (2006.01); C07K 14/255 (2006.01); A61K 39/295 (2006.01); C12N 7/04 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/285 (2013.01); A61K 39/295 (2013.01); A61K 39/39 (2013.01); C07K 14/255 (2013.01); C12N 7/045 (2013.01); A61K 2039/53 (2013.01); A61K 2039/55516 (2013.01); A61K 2039/55544 (2013.01); A61K 2039/55594 (2013.01); A61K 2039/57 (2013.01); A61K 2039/572 (2013.01); A61K 2039/58 (2013.01); A61K 2039/6031 (2013.01); A61K 2039/6068 (2013.01); A61K 2039/64 (2013.01); C12N 2700/00 (2013.01); C12N 2710/24143 (2013.01);
Abstract
Provided herein are immunogenic compositions comprising a recombinant modified vaccinia virus Ankara (MVA) comprising a nucleic acid sequence encoding a flagellin, and a nucleic acid sequence encoding a heterologous disease-associated antigen, wherein the immunogenic composition induces increased T-cell and antibody mediated immune responses specific for the heterologous disease-associated antigen when administered to a subject, e.g. a human subject, and related methods and uses.