The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 24, 2019

Filed:

Jan. 07, 2016
Applicants:

The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);

Colorado State University Research Foundation, Fort Collins, CO (US);

Inventors:

Nadya I. Tarasova, Frederick, MD (US);

Mercedes Gonzalez-Juarrero, Fort Collins, CO (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/20 (2006.01); A61K 45/06 (2006.01); A61K 38/17 (2006.01); A61K 9/00 (2006.01); A61K 9/12 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01);
U.S. Cl.
CPC ...
A61K 38/2066 (2013.01); A61K 9/007 (2013.01); A61K 9/12 (2013.01); A61K 38/1709 (2013.01); A61K 38/1793 (2013.01); A61K 45/06 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01);
Abstract

The invention provides a method of treating pathogenic bacterial infection (e.g., tuberculosis infection) in an animal comprising administering a peptide-based inhibitor of the STAT3-IL10 pathway or a nucleic acid encoding the peptide-based inhibitor to the animal. The invention also provides methods of treating chronic granulomatous disease and Wegener's granulomatosis in an animal comprising administering a peptide-based inhibitor of the STAT3-IL10 pathway or a nucleic acid encoding the peptide-based inhibitor to the animal.


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