The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 24, 2019
Filed:
Jun. 01, 2016
Applicant:
University of Kentucky Research Foundation, Lexington, KY (US);
Inventor:
Vivek M. Rangnekar, Lexington, KY (US);
Assignee:
University of Kentucky Research Foundation, Lexington, KY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4706 (2006.01); A61P 35/04 (2006.01); A61P 35/00 (2006.01); A61K 31/122 (2006.01); A61K 31/192 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4706 (2013.01); A61K 31/122 (2013.01); A61K 31/192 (2013.01); A61P 35/00 (2018.01); A61P 35/04 (2018.01);
Abstract
Described herein are methods for treating cancer in a subject in need thereof by administering chloroquine, or a salt or prodrug thereof, optionally with another agent that promotes Par-4 production to induce prostate apoptosis response-4 (Par-4) production by host cells, particularly non-cancerous host cells, to promote apoptosis in cancer cells, including androgen insensitive prostate cancer cells.