The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 17, 2019
Filed:
Mar. 04, 2015
Konica Minolta, Inc., Tokyo, JP;
Hideki Gouda, Tokyo, JP;
Masaru Takahashi, Musashino, JP;
KONICA MINOLTA, INC., Tokyo, JP;
Abstract
Provided are: a phosphor-integrated nanoparticle labeling agent which is capable of yielding a sufficient signal intensity even when its final concentration in an immunofluorescent staining reaction system is low (e.g., 0.02 nM) and enables to obtain an immunofluorescently stained image with reduced noise by inhibiting non-specific adsorption of a probe biological substance and a label to substances other than a detection subject; and an immunostaining method using the same. The phosphor-integrated nanoparticle labeling agent is a set which includes: a probe biological substance, which is linked to a first binding group substance A via a first hydrophilic polymer-derived spacerhaving a length of 30 Å to 1,000 Å and specifically binds to a biomolecule; and a phosphor-integrated nanoparticle, which has a second binding group substance B capable of specifically binding to the first binding group substance A.