The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 17, 2019

Filed:

Aug. 05, 2016
Applicant:

Gamamabs Pharma, Toulouse, FR;

Inventors:

Olivier Dubreuil, Toulouse, FR;

Jean-Marc Barret, Toulouse, FR;

Jean-François Prost, Toulouse, FR;

Delphine Desigaud, Toulouse, FR;

Assignee:

GAMAMABS PHARMA SA, Toulouse, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); C07K 16/28 (2006.01); A61K 51/10 (2006.01); A61K 47/68 (2017.01);
U.S. Cl.
CPC ...
G01N 33/57415 (2013.01); A61K 47/6803 (2017.08); A61K 47/6849 (2017.08); A61K 47/6869 (2017.08); A61K 51/1036 (2013.01); A61K 51/1093 (2013.01); C07K 16/2869 (2013.01); G01N 33/57434 (2013.01); G01N 33/57442 (2013.01); G01N 33/57449 (2013.01); C07K 2317/24 (2013.01); C07K 2317/41 (2013.01); C07K 2317/73 (2013.01); C07K 2317/77 (2013.01); C07K 2317/92 (2013.01); G01N 2333/72 (2013.01);
Abstract

This invention relates to antibody drug conjugates (ADC), antibody conjugates (AC) and novel antibodies. Particularly, the ADC, AC and antibodies disclosed herein specifically bind to the human anti-Müllerian hormone type II receptor (AMHR-II) and can be used to treat and/or identify AMHR-II expressing cancers, such as prostate cancer, breast cancer and gynecologic cancers expressing AMHR-II, such as ovarian cancer, in particular metastatic ovarian cancer, serous cancer, hypernephroma, endometrioid, colloidal epithelium, prostate cancer, germ cell cancer, endometrial cancer, mixed Müllerian malignant tumor of the uterus, leiomyosarcoma, or endometrial stromal sarcoma.


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