The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 17, 2019

Filed:

Oct. 30, 2015
Applicant:

California Institute of Technology, Pasadena, CA (US);

Inventors:

Stephen R. Quake, San Marino, CA (US);

Marc A. Unger, South San Francisco, CA (US);

Hou-Pu Chou, Sunnyvale, CA (US);

Todd A. Thorsen, Pasadena, CA (US);

Axel Scherer, Laguna Beach, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 15/06 (2006.01); G01N 33/00 (2006.01); G01N 33/48 (2006.01); B01D 57/02 (2006.01); B01D 61/18 (2006.01); B01D 61/28 (2006.01); B01D 63/08 (2006.01); B01F 5/06 (2006.01); B01F 11/00 (2006.01); B01F 13/00 (2006.01); B01F 13/10 (2006.01); B01L 3/00 (2006.01); F04B 43/04 (2006.01); F16K 99/00 (2006.01); G01N 27/447 (2006.01); G01N 33/50 (2006.01); C12M 3/06 (2006.01); C12M 1/34 (2006.01); G01N 33/569 (2006.01); B01F 7/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/00 (2013.01); B01D 57/02 (2013.01); B01D 61/18 (2013.01); B01D 61/28 (2013.01); B01D 63/081 (2013.01); B01D 63/088 (2013.01); B01F 5/0646 (2013.01); B01F 5/0647 (2013.01); B01F 11/0071 (2013.01); B01F 13/0059 (2013.01); B01F 13/1013 (2013.01); B01F 13/1022 (2013.01); B01L 3/50273 (2013.01); B01L 3/502715 (2013.01); B01L 3/502738 (2013.01); B01L 3/502746 (2013.01); B01L 3/502761 (2013.01); C12M 23/16 (2013.01); C12M 41/46 (2013.01); F04B 43/043 (2013.01); F16K 99/0001 (2013.01); F16K 99/0009 (2013.01); F16K 99/0015 (2013.01); F16K 99/0046 (2013.01); F16K 99/0048 (2013.01); F16K 99/0051 (2013.01); F16K 99/0059 (2013.01); G01N 15/06 (2013.01); G01N 27/44743 (2013.01); G01N 27/44791 (2013.01); G01N 33/5005 (2013.01); G01N 33/5008 (2013.01); G01N 33/56966 (2013.01); B01D 2313/08 (2013.01); B01D 2313/90 (2013.01); B01F 7/00 (2013.01); B01L 3/502707 (2013.01); B01L 2200/0631 (2013.01); B01L 2200/10 (2013.01); B01L 2300/0627 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0864 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/0877 (2013.01); B01L 2300/0887 (2013.01); B01L 2300/123 (2013.01); B01L 2300/1822 (2013.01); B01L 2300/1827 (2013.01); B01L 2400/0415 (2013.01); B01L 2400/0481 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/0633 (2013.01); B01L 2400/0655 (2013.01); B01L 2400/082 (2013.01); F16K 2099/008 (2013.01); F16K 2099/0074 (2013.01); F16K 2099/0084 (2013.01); Y10T 436/11 (2015.01); Y10T 436/117497 (2015.01); Y10T 436/25 (2015.01); Y10T 436/2575 (2015.01); Y10T 436/25375 (2015.01);
Abstract

The present invention provides microfluidic devices and methods for using the same. In particular, microfluidic devices of the present invention are useful in conducting a variety of assays and high throughput screening. Microfluidic devices of the present invention include elastomeric components and comprise a main flow channel; a plurality of branch flow channels; a plurality of control channels; and a plurality of valves. Preferably, each of the valves comprises one of the control channels and an elastomeric segment that is deflectable into or retractable from the main or branch flow channel upon which the valve operates in response to an actuation force applied to the control channel.


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