The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 17, 2019

Filed:

Jun. 21, 2018
Applicants:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Roche Diabetes Care, Inc., Indianapolis, IN (US);

Inventors:

Peter Kratzsch, Penzberg, DE;

Mara Boenitz-Dulat, Tutzing, DE;

Daniela Beck, Penzberg, DE;

Thomas Streidl, Seeshaupt, DE;

Stacy Hunt DuVall, Indianapolis, IN (US);

Assignees:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Roche Diabetes Care, Inc., Indianapolis, IN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/04 (2006.01); C12Q 1/54 (2006.01); C12Q 1/32 (2006.01);
U.S. Cl.
CPC ...
C12N 9/0006 (2013.01); C12Q 1/32 (2013.01); C12Q 1/54 (2013.01); C12Y 101/0103 (2013.01);
Abstract

The present disclosure relates to a mutant 3-hydroxybutyrate dehydrogenase (3-HBDH) with improved performance relative to the wild-type 3-HBDH, a nucleic acid encoding the mutant 3-HBDH, a cell having the mutant 3-HBDH or the nucleic acid, and/or a method of determining the amount or concentration of 3-hydroxybutyrate in a sample. Also disclosed is the use of the mutant 3-HBDH for determining the amount or concentration of 3-hydroxybutyrate in a sample, and a device for determining the amount or concentration of 3-hydroxybutyrate in a sample.


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