The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 17, 2019
Filed:
Aug. 21, 2015
Applicant:
National Cheng Kung University, Tainan, TW;
Inventor:
Woei-Jer Chuang, Tainan, TW;
Assignee:
NATIONAL CHENG KUNG UNIVERISTY, Tainan, TW;
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/46 (2006.01); C12N 9/64 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/46 (2013.01); C12N 9/6418 (2013.01); A61K 38/00 (2013.01);
Abstract
Disintegrin variants that bind specifically to one or more of α5β1 and αv integrins, such as αvβ1, αvβ3, αvβ5, αvβ6 and αvβ8, but with reduced binding activity to αIIbβ3, are described. Also described are uses of the disintegrin variants for the treatment or prevention of a disease associated with an αv integrin or an α5β1 integrin.