The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 17, 2019
Filed:
Jul. 19, 2017
Applicant:
The Regents of the University of Colorado, a Body Corporate, Denver, CO (US);
Inventors:
Xuedong Liu, Niwot, CO (US);
Gan Zhang, Niwot, CO (US);
Daniel Chuen-Fong Chan, Denver, CO (US);
Anthony D. Piscopio, Longmont, CO (US);
Assignee:
The Regents of the University of Colorado, A Body Corporate, Denver, CO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 513/04 (2006.01); C07D 473/34 (2006.01); C07D 487/04 (2006.01); C07D 473/16 (2006.01);
U.S. Cl.
CPC ...
C07D 513/04 (2013.01); C07D 473/16 (2013.01); C07D 473/34 (2013.01); C07D 487/04 (2013.01);
Abstract
The present invention relates to novel hydroxamic acids which are specific histone deacetylase (HDAC) inhibitors and/or TTK/Mps1 kinase inhibitors, including pharmaceutically acceptable salts thereof, which are useful for modulating HDAC and/or TTK/Mps1 kinase activity, pharmaceutical compositions comprising these compounds, and processes for their preparation.