The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 17, 2019

Filed:

Jun. 21, 2018
Applicants:

Zhejiang Hisun Pharmaceutical Co., Ltd., Taizhou, Zhejiang, CN;

Shanghai Institute of Pharmaceutical Industry, Shanghai, CN;

Inventors:

Fuli Zhang, Shanghai, CN;

Zhezhou Yang, Shanghai, CN;

Rusheng Bao, Taizhou, CN;

Weiwei Xu, Taizhou, CN;

Hua Bai, Taizhou, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 237/22 (2006.01); C07D 471/04 (2006.01); A61K 31/4985 (2006.01); C07C 231/02 (2006.01); C07C 231/14 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/4985 (2013.01); C07C 231/02 (2013.01); C07C 231/14 (2013.01); C07C 237/22 (2013.01);
Abstract

Intermediate compounds for the preparation of Praziquantel are provided. In particular, the intermediate compounds provided include a compound of formula (IV) and a compound of formula (V). Also provided are processes for preparing the intermediate compounds. Additionally, the raw materials are inexpensive and easy to obtain, the key intermediates are easy to prepare, and the total reaction yield and purity of the obtained target compound Praziquantel is high, so that industrialized mass production of Praziquantel using the intermediate compounds is easy to achieve.


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