The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 17, 2019

Filed:

Mar. 25, 2019
Applicants:

National Guard Health Affairs, Riyadh, SA;

King Saud Bin Abdulaziz University for Health Sciences, Riyadh, SA;

King Abdullah International Medical Research Center, Riyadh, SA;

Inventor:

Mamdooh Alqathami, Riyadh, SA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/18 (2006.01); A61K 49/12 (2006.01); A61K 51/12 (2006.01); A61K 51/06 (2006.01);
U.S. Cl.
CPC ...
A61K 49/1818 (2013.01); A61K 49/12 (2013.01); A61K 51/06 (2013.01); A61K 51/1213 (2013.01); A61K 51/1282 (2013.01);
Abstract

A biocompatible curable composition and a method of detecting a border of a tumor, a tissue of interest, or both including injecting the biocompatible curable composition and contacting the border of a tumor or a tissue, the biocompatible curable composition crosslinks to form a three-dimensional cured nanocomposite, and imaging the three-dimensional (3D) cured nanocomposite, and imaging the 3D cured nanocomposite by at least one of MRI, CT, ultrasound, and X-ray, to detect the border of the tumor or the tissue of interest or track tumor motion during radiotherapy treatment. The biocompatible curable composition comprising an organic polymer having a hydrolysable functional group, a metallic nanoparticle, and a polar or a non-polar solvent. A brachytherapy strand consisting of a biocompatible curable composition and a radio-isotope seed. The biocompatible curable composition is shaped into an elongated cylinder and forms a 3D cured nanocomposite with a radio-isotope seed embedded.


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