The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 17, 2019

Filed:

Mar. 18, 2016
Applicant:

The University Court of the University of Edinburgh, Edinburgh, Midlothian, GB;

Inventors:

Mark Bradley, Midlothian, GB;

Sunay Vijaykumar Chankeshwara, Midlothian, GB;

Alicia Megia-Fernandez, Midlothian, GB;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 10/00 (2006.01); A61B 5/00 (2006.01); A61B 8/00 (2006.01); A61K 47/54 (2017.01); A61K 49/00 (2006.01); C12Q 1/37 (2006.01); G01N 33/58 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
A61K 47/556 (2017.08); A61K 49/0041 (2013.01); A61K 49/0056 (2013.01); C12Q 1/37 (2013.01); G01N 33/582 (2013.01); G01N 33/574 (2013.01); G01N 2333/96486 (2013.01); G01N 2800/085 (2013.01); G01N 2800/102 (2013.01); G01N 2800/7052 (2013.01);
Abstract

An optical probe is presented comprising at least one fluorophore connected to at least one quencher by an enzyme cleavable peptide sequence; the or each fluorophore being substantially fluorescently quenched by the at least one quencher when connected to the enzyme cleavable peptide sequence; the or each fluorophore is separated from the at least one quencher when the enzyme cleavable peptide sequence of the at least one probe element is cleaved; and the enzyme cleavable peptide sequence is selectively cleavable by one or more matrix metalloproteinase (MMP). Methods of use of the optical probe are also presented.


Find Patent Forward Citations

Bradley, Mark. (2019). Optical probes for matrix metalloproteinases (U.S. Patent No. 10507247). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10507247

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…