The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 17, 2019
Filed:
Jul. 13, 2016
Inserm (Institut National DE LA Santé ET DE LA Recherche Médicale), Paris, FR;
Université Paris Descartes, Paris, FR;
Centre National DE LA Recherche Scientifique (Cnrs), Paris, FR;
Université Pierre ET Marie Curie (Paris 6), Paris, FR;
Université Paris Diderot—paris 7, Paris, FR;
Université Paris-sud, Orsay, FR;
Sorbonne Universite, Paris, FR;
Roberto Mallone, Paris, FR;
Slobodan Culina, Paris, FR;
Nimesh Gupta, Paris, FR;
Sebastien Lacroix-Desmazes, Paris, FR;
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), Paris, FR;
UNIVERSITE PARIS DESCARTES, Paris, FR;
UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), Paris, FR;
UNIVERSITE PARIS DIDEROT—PARIS 7, Paris, FR;
Abstract
The present invention relates to methods and pharmaceutical compositions of inducing immune tolerance by mucosal vaccination with Fc-coupled antigens. In particular, the present invention relates to a method for inducing tolerance to one antigen of interest in a subject in need thereof, comprising the mucosal administration to the subject of a therapeutically effective amount of a recombinant chimeric construct comprising a FcRn targeting moiety and an antigen-containing moiety.