The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 10, 2019

Filed:

Jan. 31, 2013
Applicants:

Cardiac Pacemakers, Inc., St. Paul, MN (US);

Musc Foundation for Research Development, Charleston, SC (US);

Inventors:

Craig M. Stolen, New Brighton, MN (US);

Timothy E. Meyer, North Oaks, MN (US);

Milan Seth, Minneapolis, MN (US);

Francis G. Spinale, Blythewood, SC (US);

Nicholas David Wold, Arden Hills, MN (US);

Assignees:

Cardiac Pacemakers, Inc., St. Paul, MN (US);

MUSC Foundation for Research Development, Charleston, SC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); A61B 5/00 (2006.01); A61B 5/07 (2006.01); A61B 5/145 (2006.01); A61N 1/362 (2006.01); A61N 1/39 (2006.01); A61N 1/365 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6893 (2013.01); A61B 5/0031 (2013.01); A61B 5/076 (2013.01); A61B 5/14503 (2013.01); A61B 5/14546 (2013.01); A61B 5/686 (2013.01); A61N 1/3627 (2013.01); A61N 1/36557 (2013.01); A61N 1/3956 (2013.01); G01N 2800/52 (2013.01);
Abstract

Embodiments of the disclosure are related to systems and methods for utilizing biomarker panel data with respect to medical devices and methods, amongst other things. In an embodiment, the disclosure can include a method of predicting the likelihood of response to CRT therapy. The method can include quantifying levels of one or more biomarkers in a biological sample of a patient, analyzing the quantified levels to determine response to CRT therapy, wherein a panel of biomarkers includes at least two selected from the group consisting of CRP, SGP-130, sIL-2R, sTNFR-II, IFNg, BNP, sST2, MMP-2, MMP-9, TIMP-1, TIMP-2, TIMP-4. Other embodiments are also included herein.


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