The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 2019
Filed:
Apr. 30, 2014
Applicants:
Universite DE Montreal, Montreal, CA;
Universite Laval, Quebec, CA;
Inventors:
Brian Thomas Wilhelm, Montreal, CA;
Frederic Barabe, Quebec, CA;
Assignees:
UNIVERSITE DE MONTREAL, Montréal QC, CA;
UNIVERSITÉ LAVAL, Québec QC, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); C07K 16/18 (2006.01); C07K 16/28 (2006.01); C07K 16/40 (2006.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); C07K 16/18 (2013.01); C07K 16/2827 (2013.01); C07K 16/40 (2013.01); G01N 33/57426 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/16 (2013.01);
Abstract
Methods for the diagnosis of leukemias, and more specifically AML, such as MLL-AF9 AML, in a subject, based on the assessment of the expression or activity of one or more of the genes listed in Tables 1 and 2 are disclosed. The use of antibodies or antigen-binding fragments thereof that bind to one or more of proteins showing preferential expression at the cell surface of AML leukemic cells for treating AML is also disclosed.