The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 10, 2019

Filed:

May. 04, 2017
Applicant:

Indiana University Research and Technology Corporation, Indianapolis, IN (US);

Inventors:

Trevor Douglas, Bloomington, IN (US);

Benjamin Harold Schwarz, Eureka, MT (US);

Ranjit Koliyatt, Mount Prospect, IL (US);

Masaki Uchida, Bloomington, IN (US);

John Alexander Avera, Spencer, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); C12N 15/00 (2006.01); C12P 21/08 (2006.01); C07K 1/00 (2006.01); C12N 15/62 (2006.01); C07K 14/435 (2006.01); C12N 15/10 (2006.01); C12N 15/63 (2006.01); C12Q 1/68 (2018.01); C07K 14/705 (2006.01); C07K 19/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/62 (2013.01); C07K 14/435 (2013.01); C07K 14/70578 (2013.01); C12N 15/1062 (2013.01); C12N 15/1075 (2013.01); C12N 15/63 (2013.01); C12Q 1/68 (2013.01); C07K 19/00 (2013.01); C07K 2319/00 (2013.01); C12N 15/00 (2013.01);
Abstract

The invention provides a fusion protein comprising an antigen binding domain linked to a bacteriophage decoration (Dec) protein along with a polynucleotide comprising the nucleic acid sequence of the fusion protein and a vector comprising the polynucleotide. Additionally, the invention provides a composition comprising the fusion protein and a virus-like particle (VLP), and a method of treating a disease in a mammal comprising administering a therapeutically effective amount of the composition to the mammal. The invention also provides a method of vaccinating against a disease comprising administering a composition comprising the fusion protein and a VLP encapsulating a protein.


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