The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 10, 2019

Filed:

Apr. 09, 2018
Applicants:

Hoffmann-la Roche Inc., Nutley, NJ (US);

Ptc Therapeutics Inc., South Plainfield, NJ (US);

Inventors:

Amal Dakka, Whitehouse Station, NJ (US);

Luke Green, Basel, CH;

Gary Karp, Princeton Junction, NJ (US);

Jana Narasimhan, Scotch Plains, NJ (US);

Nikolai Naryshkin, East Brunswick, NJ (US);

Emmanuel Pinard, Linsdorf, FR;

Hongyan Qi, Plainsboro, NJ (US);

Hasane Ratni, Habsheim, FR;

Nicole Risher, Hillsborough, NJ (US);

Marla Weetall, Morristown, NJ (US);

Matthew Woll, Dunellen, NJ (US);

Assignees:

Hoffmann—La Roche Inc., Nutley, NJ (US);

PTC Therapeutics Inc., South Plainfield, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 519/00 (2006.01); C07D 487/10 (2006.01); C07D 263/56 (2006.01); C07D 471/04 (2006.01); C07D 413/12 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 519/00 (2013.01); C07D 263/56 (2013.01); C07D 413/12 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 487/10 (2013.01);
Abstract

The present invention provides compounds of formula (I) wherein A, B, X, Y, R1 and R2 are as described herein, as well as pharmaceutically acceptable salts thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments.


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