The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 2019
Filed:
Sep. 19, 2018
Applicant:
Vanderbilt University, Nashville, TN (US);
Inventors:
Stephen W. Fesik, Nashville, TN (US);
Shaun R. Stauffer, Brentwood, TN (US);
James M. Salovich, Nashville, TN (US);
William P. Tansey, Brentwood, TN (US);
Feng Wang, Nashville, TN (US);
Jason Phan, Nashville, TN (US);
Edward T. Olejniczak, Nashville, TN (US);
Assignee:
Vanderbilt University, Nashville, TN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61P 35/02 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61P 35/02 (2018.01);
Abstract
Described are N-(6-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-2-yl)-2,3-dihydro-1H-inden-1-yl)benzamide and acetamide-containing compounds that inhibit WDR5 and associated protein-protein interactions, pharmaceutical compositions including the compounds, and methods of using the compounds and compositions for treating disorders and conditions in a subject.