The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 2019
Filed:
Jun. 22, 2017
Eisai R&d Management Co., Ltd., Tokyo, JP;
Yuta Suzuki, Ibaraki, JP;
Yoshinori Takahashi, Ibaraki, JP;
Eisai R&D Management Co., Ltd., Tokyo, JP;
Abstract
The present invention provides a cationic lipid which is able to be used for nucleic acid delivery to the cytoplasm. A cationic lipid according to the present invention is, for example, a compound represented by formula (1a) or a pharmaceutically acceptable salt thereof. (In formula (1a), each of Land Lindependently represent an alkylene group having 3-10 carbon atoms; each of Rand Rindependently represent an alkyl group having 4-22 carbon atoms or an alkenyl group having 4-22 carbon atoms; Xrepresents a single bond or —CO—O—; and ring P represents one of formulae (P-1) to (P-5).) (In formulae (P-1) to (P-5), Rrepresents an alkyl group having 1-3 carbon atoms.)