The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 2019
Filed:
Jul. 12, 2012
Applicants:
R. Yongxin Zhao, Zhengzhou, CN;
Yue Zhang, Shenzhen, CN;
Yourang MA, Zhengzhou, CN;
Inventors:
Assignee:
HANGZHOU DAC BIOTECH CO., LTD., Hangzhou, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 207/40 (2006.01); A61K 45/06 (2006.01); A61K 47/68 (2017.01); A61K 47/64 (2017.01);
U.S. Cl.
CPC ...
C07D 207/40 (2013.01); A61K 45/06 (2013.01); A61K 47/64 (2017.08); A61K 47/6803 (2017.08); A61K 47/6811 (2017.08); A61K 47/6849 (2017.08); A61K 47/6851 (2017.08); A61K 47/6855 (2017.08); A61K 47/6863 (2017.08); A61K 47/6867 (2017.08); Y02A 50/412 (2018.01); Y02A 50/416 (2018.01);
Abstract
A conjugate of a potent cytotoxic agent with a cell-surface receptor binding molecule having a formula (I), wherein T, L, m, n, Y, R, R, R, R, R, R, R, R, R, R, R, and Rare defined herein, can be used for targeted treatment of cancer, autoimmune disease, and infectious disease.