The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 10, 2019

Filed:

Jan. 31, 2019
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Dino Di Carlo, Los Angeles, CA (US);

Daniel R. Gossett, Los Angeles, CA (US);

Henry T. K. Tse, San Francisco, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01D 12/00 (2006.01); B01L 3/00 (2006.01); G01N 15/14 (2006.01);
U.S. Cl.
CPC ...
B01D 12/00 (2013.01); B01L 3/502761 (2013.01); B01L 3/502776 (2013.01); B01L 3/502746 (2013.01); B01L 2200/0652 (2013.01); B01L 2300/0816 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/084 (2013.01); G01N 2015/149 (2013.01);
Abstract

A method of exchanging fluids with suspended particles includes providing a microfluidic device with a first inlet channel operatively coupled to a source of particles and a second inlet channel operatively coupled to an exchange fluid. A transfer channel is connected at a proximal end to the first inlet channel and the second inlet channel. First and second outlet channels are connected to a distal end of the transfer channel. The source of particles is flowed at a first flow rate into the first inlet channel while the exchange fluid is flowed at a second flow rate into the second inlet channel wherein the ratio of the second flow rate to the first flow rate is at least 1.5. Particles are collected in one of the first and second outlet channels while fluid substantially free of particles is collected in the other of the first and second outlet channels.


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