The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 10, 2019

Filed:

Aug. 21, 2015
Applicant:

The Regents of the University of Michigan, Ann Arbor, MI (US);

Inventors:

Thomas D. Wang, Ann Arbor, MI (US);

Juan Zhou, Ann Arbor, MI (US);

Bishnu P. Joshi, Ann Arbor, MI (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); G01N 33/574 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 49/0056 (2013.01); A61K 45/06 (2013.01); A61K 49/0032 (2013.01); A61K 49/0043 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); G01N 33/57419 (2013.01); G01N 2800/52 (2013.01);
Abstract

The present invention is directed to EGFR-specific peptide reagents, methods for detecting pre-cancer, early cancer and/or cancer using the peptide reagents, and methods for targeting pre-cancer cells, early cancer cells and/or cancer cells using the peptide reagents. In one aspect, the disclosure provides reagents consisting essentially of a peptide QRHKPRE (SEQ ID NO: 1), HAHRSWS (SEQ ID NO: 2), YLTMPTP (SEQ ID NO: 3), TYPISFM (SEQ ID NO: 4), KLPGWSG (SEQ ID NO: 5), IQSPHFF (SEQ ID NO: 6), YSIPKSS (SEQ ID NO: 7), SHRNRPRNTQPS (SEQ ID NO: 8), NRHKPREKTFTD (SEQ ID NO: 9).


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