The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 10, 2019

Filed:

Jul. 14, 2017
Applicant:

The United States of America, As Represented BY the Secretary, Dept. of Health and Human Services, Rockville, MD (US);

Inventors:

Stephen S. Whitehead, Bethesda, MD (US);

Brian R. Murphy, Bethesda, MD (US);

Kathryn A. Hanley, Las Cruces, NM (US);

Joseph E. Blaney, Gettysburg, PA (US);

Ching-Juh Lai, Bethesda, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); C12N 7/00 (2006.01); A61K 39/295 (2006.01); C12Q 1/70 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); A61K 39/295 (2013.01); C12N 7/00 (2013.01); C12Q 1/701 (2013.01); A61K 2039/5252 (2013.01); A61K 2039/5254 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/54 (2013.01); A61K 2039/575 (2013.01); A61K 2039/70 (2013.01); C12N 2770/24121 (2013.01); C12N 2770/24134 (2013.01); C12N 2770/24161 (2013.01); C12N 2770/24162 (2013.01); C12N 2770/24171 (2013.01); C12Q 2600/156 (2013.01); G01N 2333/18 (2013.01); G01N 2500/10 (2013.01); Y02A 50/386 (2018.01);
Abstract

A menu of mutations was developed that is useful in fine-tuning the attenuation and growth characteristics of dengue virus vaccines.


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