The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 10, 2019

Filed:

Dec. 03, 2015
Applicant:

University of Cincinnati, Cincinnati, OH (US);

Inventors:

Christy Holland, Cincinnati, OH (US);

Jason Raymond, Cincinnati, OH (US);

Jonathan Sutton, Cincinnati, OH (US);

Assignee:

University of Cincinnati, Cincinnati, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 41/00 (2006.01); A61K 9/127 (2006.01); A61K 33/00 (2006.01); A61K 9/00 (2006.01); A61K 47/69 (2017.01); A61K 49/22 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
A61K 33/00 (2013.01); A61K 41/0028 (2013.01); A61K 9/0019 (2013.01); A61K 9/1271 (2013.01); A61K 9/1278 (2013.01);
Abstract

Echogenic liposomes (ELIP) formulated with an at least partially pegylated phospholipid bi-layer shell, encapsulated nitric oxide, and encapsulated perfluorocarbon of the formula CxFy in a ratio of about 1:1 by volume, wherein X is greater than or equal to 3, are disclosed, along with methods for treating a patients suffering from cardiovascular disease by administering the ELIP at a site remote from the target diseased section, monitoring presence of the ELIP at the target diseased section, and administering ultrasound upon detection of presence such that bioactive NO is released at the target diseased section.


Find Patent Forward Citations

Loading…