The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 10, 2019

Filed:

Dec. 30, 2013
Applicants:

Hadasit Medical Research Services and Development Ltd., Jerusalem, IL;

B.g. Negev Technologies & Applications Ltd., AT Ben-gurion University, Beer-Sheva, IL;

Inventors:

Smadar Cohen, Beer-Sheva, IL;

Yaron Ilan, Kfar-Tavor, IL;

Eyal Shteyer, Mevaseret Zion, IL;

Ami Ben-Ya'Acov, Jerusalem, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/734 (2006.01); A61K 31/167 (2006.01); A61K 9/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/734 (2013.01); A61K 9/0053 (2013.01); A61K 31/167 (2013.01); A61K 45/06 (2013.01);
Abstract

Compositions comprising an alginate, a source of sodium ions and a carrier (e.g., a pharmaceutically acceptable carrier), which are characterized by reduced association of the alginate chains and hence by at least one of: (i) a zeta potential weaker than −25 mV, at a concentration of 0.5% (w/v) alginate in the carrier; and (ii) a diffusion coefficient of at least 10cm/second, at a concentration of 0.5% (w/v) alginate in the carrier, are disclosed. Also disclosed are uses of the composition and methods utilizing the composition for treating inflammatory bowel disease; liver damage, diseases and disorders, for treating a medical condition treatable by a hepatotoxic agent and for reducing or preventing liver damage, including liver damage caused by a hepatotoxic agent.


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